Laptop vs desktop free essay sample

A computer is an electronic device to perform a set of arithmetic or logical operations with a given set of instructions. Computers play a crucial role in our daily life. Now-a-days, as the technology increases day by day, computers are classified into two types, namely, desktop computer and laptop computer. The similarities and differences of a desktop computer and a laptop computer are to be discussed. Firstly, cost. Desktop computers are cost efficient. There is wide range of desktop computers, but the least configured computer is relatively cheap. For example, desktop with RAM 4 GB, Hard disk 500 GB start as low as $300. There is a large range of laptop computers, but the best configured laptop can be relatively higher. For example, a powerful laptop with higher speed, RAM, Hard disk start around $600 or more, depending on the brand. Secondly, size. Desktop computers are large in size which consists of a monitor, a keyboard, a mouse and a CPU. We will write a custom essay sample on Laptop vs desktop or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page These are united together to use. A desktop isn’t movable easily. They are designed to use in a single location. For example, we can’t carry a desktop to the restaurant and theater. Components of a laptop are connected into a single device. They are around 11† to 18† in size and can be carried easily in a backpack. Laptops are portable due to its size. For example, we can carry a laptop to the restaurant, the theater and in the car while we travel. Thirdly, the space required to access. Desktop requires more space to set up. For accessing the desktop, we need to stick to a particular place for access. For example, a desktop cannot be used on the bed with respect to our seating position. We need to sit in a chair to access. Laptop can be used from anywhere in any manner. For example, laptop can be used on the bed, in the restaurant, in the car. Fourthly, ease in upgrading the device. Most components in a desktop are easily removable which makes easier to upgrade. The case of desktop is relatively big which makes our work easy while upgrading. RAM/Hard drive is only the component that can be upgraded in a laptop. All the other components are built-in. Fifthly, repair and spare parts. Desktop computers can be repaired easily as all the spare parts are available in most of the computer retail stores. For example, if there is a malfunction is keyboard keys we can easily replace with another by visiting a computer retail store. Finding a replacement part for laptop is difficult, as it can be ordered only in manufacturer’s online website. For example, to purchase a new battery we should visit the manufacturer’s online site and order. Both the electronic devices have advantages but if portability is a very big need of yours, best option is laptop. There are some limitations when compared to desktop computers but it is significant for most of the users. Desktop are for intensive online gaming, who just needs email access and for AUTOCAD applications.

The inflammatory phases of Atherosclerosis The WritePass Journal

The inflammatory phases of Atherosclerosis Abstract The inflammatory phases of Atherosclerosis Abstract IntroductionAimsRationale of the aimsRelated Abstract Aim This review describes recent investigations in to the impact of atherosclerosis on the vessel using four inflammatory stages eventually leading to cardiovascular complication. Research in to atherosclerosis has intensified globally as it has become one of the main reasons for increased mortality among individuals particularly within western societies. Inflammation has been established as the principal concept due to it stimulating progressive lesion development. As a result it is known as a chronic inflammatory disorder. Numerous cellular and molecular inflammatory mediators participate in the formation, development and rupture of the atherosclerotic plaque. Several experimental studies have demonstrated that monocyte- derived macrophages as well as T-lymphocytes are the most distinctive cells to accumulate within progressive plaques and induce the production of pro-inflammatory components, more recently, potential anti-inflammatory mediators have been identified in the inflammatory response. The rate of progressive plaque development varies in different types of people. Risk factors increase the development of this condition and promote the occurrence of physical symptoms on the patient. Conclusions (1) Inflammation attacks arteries systematically within phases and (2) the significance of the role of inflammatory molecules, linking inflammation to atherosclerosis. Introduction The management of cardiovascular diseases has significantly improved, however it is still not clearly understood as to why atherosclerosis remains the leading pathological cause of both morbidity and mortality in developed countries. Atherosclerosis is known to be a type of arteriosclerosis, but in addition to the hardening and narrowing of the arteries, cholesterol begins to deposit within their walls. It is a multifactorial disease which includes build up of atheromatous plaque and accumulation of more complex lesions within the arterial walls specifically in the intimal layer leading to the rupture of these vulnerable atherosclerotic plaques (Skjot-Arkil et al, 2010). This process is initiated in childhood and according to the results of PDAY   (pathobiological determinants of atherosclerosis in youth study), visible symptoms of atherosclerosis will occur between ages of 15-54 years (McGill et al.2007). Furthermore this disease can occur in both medium and large sized arteries including the aorta, carotid artery and even the smaller coronary arteries. Due to the fact that it affects multiple arterial locations, it can then lead to clinical diseases such as coronary artery disease, cerebrovascular disease, myocardial infarction. Jongstra et al. (2006) demonstrated that within the intima of VCAM-1 positive mice, local chronic inflammation predisposed to atherosclerosis. This provided further evidence to support previous studies that inflammation participates in the atherosclerotic process. Consequently, inflammation is progressively involved in the plaque formation, resulting in an inevitable stenosis (Vidal-Vanaclocha, 2009). Numerous epidemiological studies have revealed many risk factors that accelerate atherosclerosis development including age, male gender, obesity, smoking, hypertension and diabetes mellitus. Moreover, a recent study (Holvoet et al, 2007) found that a positive correlation exists between an increased amount of oxidised LDL and the quantity of calcium built up in the coronary artery. Therefore showing that increased amount of oxidised LDL is a unique risk factor for the development of atherosclerosis. The factors that facilitate this plaque formation are inflammatory mediators. As the endothelial cell is activated, this results in expression of many cell surface adhesion molecules including cytokines, chemokines, monocytes, immunoglobulins. These promote endothelial dysfunction in atherosclerosis as well as inducing foam cell formation with the assistance of macrophages. However, the functional mechanisms of cytokines in initiating and prolonging atherosclerosis are still not clearly un derstood. Aims To explore the role of inflammation in atherosclerosis To explore the mechanisms of inflammatory cell recruitment and accumulation within the plaque. To explore the function of various different mediators in this process, including both pro and anti-inflammatory mediators. Rationale of the aims To investigate the effects of the inflammatory cycle on arteries using atherosclerosis as the central condition. Hence, following the aims and objectives of the literature review, an overview of numerous meta-analyses of mediator involvement in this process is provided. This would be performed by reviewing the most relevant literature for the past five years using Pubmed, Science direct and Google Scholar. Table 1 Methodical reviews on the involvement of inflammatory components within the development of atherosclerosis. Type of component Mediator Experimental source Inflammatory effect Effect on Atherosclerosis Author, year Immunoglobulin ICAM-1 Human plasma Human aortic SMC Human aortic endothelial cells ↑ ↑ ↑ ↑ ↑ ↑ Bielinski et al, 2008 Burton et al, 2009 Roth et al, 2007 Immunoglobulin VCAM-1 Human plasma Human aortic endothelial cells ↑ ↑ ↑ ↑ Bielinski et al, 2008 Roth et al, 2007 Cytokine TNF-alpha APoE-/- mice ↓ ↓ Bhaskar et el, 2011 Cytokine IFN-gamma Human RNA ↑ ↑ Niedzielska and Cierpka, 2010 Cytokine M-CSF Human platelets ↑ Siezer et al, 2010 Cytokine IL-6 Human aortic endothelial cells Human Plasma APoE-/- mice ↑ ↑ ↓ ↑ ↑ ↓ Roth et al, 2007 Hoshi et al, 2008 Bhaskar et al, 2011 Cytokine IL-1 (beta) Human aortic SMC APoE-/- mice ↑ ↑ ↑ ↑ Burton et al, 2009 Bhaskar et al, 2011 Chemokine CXCL16 Human and murine   macrophages APoE-/- ↑ ↑ ↑ Lehrke et al, 2007 Wen-Yi et al, 2011 Chemokine CXCR6 Human and murine macrophages ↑ ↑ Lehrke et al, 2007 Ligand CD40 L Human umbilical vein endothelial cells ↑ ↑ Chakrabarti et al, 2010 Monocyte Protein MCP-1 Human aortic endothelial cellsAPoE-/- mice ↑ ↓ ↑ ↓ Roth et al, 2007 Bhaskar et al, 2011 Toll-like receptor TLR-2 ↑ Doherty et al, 2006

Battle of Badajoz - Peninsular War

Battle of Badajoz - Peninsular War Battle of Badajoz - Conflict: The Battle of Badajoz was fought from March 16 to April 6, 1812 as part of the Peninsular War, which was in turn part of the Napoleonic Wars (1803-1815). Armies Commanders: British Earl of Wellington25,000 men French Major General Armand Philippon4,742 men Battle of Badajoz - Background: Following his victories at Almeida and Ciudad Rodrigo, the Earl of Wellington moved south towards Badajoz with the goal of securing the Spanish-Portuguese frontier and improving his lines of communication with his base at Lisbon. Arriving at the city on March 16, 1812, Wellington found it held by 5,000 French troops under the command of Major General Armand Philippon. Long aware of Wellingtons approach, Philippon had significantly improved the Badajozs defenses and had laid in large supplies of provisions. Battle of Badajoz - The Siege Begins: Outnumbering the French nearly 5-to-1, Wellington invested the city and began construction of siege trenches. As his troops pushed their earthworks towards Badajozs walls, Wellington brought up his heavy guns and howitzers. Knowing that it was only a matter of time until the British reached and breached the citys walls, Philippons men launched several sorties in an attempt to destroy the siege trenches. These were repeatedly beaten back by British riflemen and infantry. On March 25, General Thomas Pictons 3rd Division stormed and captured an outer bastion know as the Picurina. The capture of the Picurina allowed Wellingtons men to expand their siege works as his guns pounded away at the walls. By March 30, breaching batteries were in place and over the next week three openings were made in the citys defenses. On March 6, rumors began to arrive in the British camp that Marshal Jean-de-Dieu Soult was marching to relieve the beleaguered garrison. Wishing to take the city before reinforcements could arrive, Wellington ordered the assault to commence at 10:00 PM that night. Moving into position near the breaches, the British waited for the signal to attack. Battle of Badajoz - The British Assault: Wellingtons plan called for the main assault to be made by the 4th Division and Craufurds Light Division, with supporting attacks from the Portuguese and British soldiers of the 3rd and 5th Divisions. As the 3rd Division moved into place, it was spotted by a French sentry who raised the alarm. With the British moving to attack, the French rushed to the walls and unleashed a barrage of musket and cannon fire into the breaches inflicting heavy casualties. As the gaps in the walls filled with British dead and wounded, they became increasingly impassable. Despite this, the British kept swarming forward pressing the attack. In the first two hours of fighting, they suffered around 2,000 casualties at the main breach alone. Elsewhere, the secondary attacks were meeting a similar fate. With his forces halted, Wellington debated calling off the assault and ordering his men to fall back. Before the decision could be made, news reached his headquarters that Pictons 3rd Division had secured a foothold on the city walls. Connecting with the 5th Division which had also managed to scale the walls, Pictons men began pushing into the city. With his defenses broken, Philippon realized that it was only a matter of time before British numbers destroyed his garrison. As the redcoats poured into Badajoz, the French conducted a fighting retreat and took refuge in Fort San Christoval just north of the city. Understanding that his situation was hopeless, Philippon surrendered the following morning. In the city, British troops went wild looting and committed a wide array of atrocities. It took nearly 72 hours for order to be completely restored. Battle of Badajoz - Aftermath: The Battle of Badajoz cost Wellington 4,800 killed and wounded, 3,500 of which were incurred during the assault. Philippon lost 1,500 dead and wounded as well as the remainder of his command as prisoners. Upon seeing the piles of British dead in the trenches and breaches, Wellington wept for the loss of his men. The victory at Badajoz secured the border between Portugal and Spain and allowed Wellington to begin advancing against the forces of Marshal Auguste Marmont in Salamanca.

No Country for Women and Pink Saris Essay Example | Topics and Well Written Essays - 500 words

No Country for Women and Pink Saris - Essay Example The film agitates women to demand better representation in organizations and government. â€Å"No Country for Women† constrains copious stories within it, which underscore the past injustices, as well as forms of discrimination meted on Indian women.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Although the caste system in Indian underlined in â€Å"No Country for Women† impacts both genders, women are often subject to more intense ridicule compared to men. Furthermore, the film shows the gender-based discrimination particularly targeted toward empowered and well-educated women. Despite many of the women acquiring good education through a formal, institutionalized system of learning, a typical Indian woman is still subject to discrimination in the workplace and the organization in general. Apparently, most organizations are structured such that power and authority revolve around men. Besides, Indian men have more cultural rights to social freedom, mobility, and autonomy outside the home compared to women. The film has effectively demonstrated how domestic responsibilities, as well as the socially and culturally specified roles, deter women from fully participating in various matters at the organizational and national level .   The second film, â€Å"Pink Saris†, is fairly long and primarily about the Gulabi Gang. A gang is a group of women standing to champion for their rights and that of other women in a feudal part of India. The film is set in Uttar Pradesh, one of the poorest and most federal areas of India. The area has a long history of patriarchy, abuse, and corruption. The Gulabi Gang, an outspoken and aggressive group of women, is fighting the system. Directed by Kim Longinotto, â€Å"Pink Saris† focuses on the women gang and their families. Apparently, women in this part of India do not have rights to equality. A typical case in point is the story of a man (in the film) who has been together with a girl for at least two years but ditched her after she becomes pregnant. The girl, evidently disconsolate and heartbroken, wants to die.   Sampat Pal, the protagonist, was married into a family while still a young girl. The family made her work strenuously hard and often beat her. In the end, she successfully manages to fight back, leaving her in-laws and ultimately becoming a champion and defender for beleaguered women across Uttar Pradesh. Rekha, a fourteen-year-old girl, is three months old and homeless. The father to her unborn child has refused to marry her because she belongs to a low caste.

Case study The global pharmaceutical industry Essay

Case study The global pharmaceutical industry - Essay Example However the wave of competition has caused shift in priorities, "many existing pharmaceutical compounds are standardized formulations that varies little in efficacy among manufacturers". The struggle for the differentiated product shall bring financial fortune to the agents of this industry, therefore major investment towards "advertising and sales force budgets have increased manifold in past years" (Sarah, 2004). As per research, less than 20 percent of the funds are allocated towards research and development expenditures. The investment towards research and development is further differentiated in terms of investment towards promising drug compounds in clinical human trials, which is less than 7 percent. The breakdown of the funds allocation is, "product introduction trials account for 5.8%; process development consumes 10% of research expenses' pre-clinical functions consumes 41%; extraction of chemical compounds for evaluation consumes 11.8%; and investment towards safety and toxicology consumes 5.4%". The new products consume more than 80% of expenditures of the research and development expenditures. The main environmental forces which has influenced the growth of this industry has been "expenditures towards research and development for each drug which typically last through a period of 10 to 15 years before a compound makes it to the market" (Michael, 2001). The approval from the relevant authorities essential for the public release of the product also dampens the growth of this industry; it takes more than 16 months for the specific product to get approved by the relevant authorities. The likelihood of clearances are also low, "only 1 in 5000 compounds will eventually be sold and less than one third of... It is expected that the pharmaceutical companies have the best potential to benefit from "aging population and increasing life expectancy rates throughout the world", the market for such products have expanded significantly, and it is predicted that by the end of current decade the concept of drugs for increase in life expectancy shall receive positive response in the poor countries of Asia and Africa, it this prediction comes out to be true than irrespective of the current wave of financial recession, this industry has positive scope towards financial development. It is known that the general understanding about health aspects is common in developed, developing and under-developing countries, therefore the sales of the pharmaceutical products shall not be confined to specific geography or class, and rather it is global business, having global outreach and market. As per research, "this business is attractive with operating profit margins exceeding 30% which is approximately twice th e S & P Industrial Index and net earnings as a percentage of sales averaging 17.9% versus 5.4% for general industry over the last 5 years". It is known that the running cost of this business is relatively lower than others; the business has "lower interest expenses, raw materials costs, tax rates and general and administrative cost as a percentage of sales when compared with most industries".

Realism in Arthur Millers Death of a Salesman :: Death Salesman essays

Realism in Arthur Miller's Death of a Salesman Realism may be defined as an attempt to reproduce the surface appearance of the life of normal people in everyday situations (Kennedy 1410). Basically realism is a situation that normal people can relate to based on their own experiences. Realism is extremely prevalent in the play Death of a Salesman. The characters in the play have real world problems. Lack of money is one of the problems, which is a problem for many people. There are also many conflicts within the family; related to each characters definition of success.   Ã‚   Willy Loman also wants his children to have a better than he has and tries to do everything he can so they will have a better life, including ending his own. One realistic situation that many people can relate to is money problems. Money is one of the main problems that Willy Loman had throughout the play. The Loman family had many purchases on payments. Linda even states â€Å"for the vacuum cleaner there’s three and a half due on the fifteenth† (Miller 1650). The Loman family was living from week to week. Every time Willy came home from a fairly successful day selling, he would think he was finally getting ahead. Willy would tell Linda how much he had made, but she would then point out how much they owed on everything. Willy then felt overwhelmed and said â€Å"My God, if business don’t pick up I don’t know what I’m gonna do!† (1650). Linda would then reassure Willy and tell him â€Å"Well, next week you’ll do better† (1650). Many people in real life have this same problem. Every time they feel they are getting ahead financially, a problem occurs and they find themselves right back where they started. Most people also have to deal with problems and conflicts within their family throughout their life. Family problems were not exempt from the characters in Death of a Salesman. Biff’s idea of success was completely opposite from Willy’s. Willy viewed success as achieving money and power; Biff however viewed success in life as being happy. Biff realized that â€Å"I’m just what I am, that’s all† (1703). Biff realized he was â€Å"a dime a dozen† (1703), but his father could not accept this reality. This situation where parents always keep telling their children what they should do with their lives is common in many families.

Enlightment Age

Enlightenment Age The Puritans believed that the sole purpose of writing was to bring the writer to debase themselves before God. And teach them the true importance of humility. Puritans wrote mainly memoirs and sermons. Puritans thought the church did have errors, but could be reformed. Growing up in the Colonial days meant strict, and God fearing obedience; education and religion were very important to them. In Mary Rowlandson writing, she was able to write about her Indian captures as somewhat kind and friendly.This is far from what we have perceived of them. Mary Rowlandson believed what most Puritans did, that God was testing her faith and humbleness. Mary believed that her final escape was a lesson to â€Å"make us the more knowledge his hand and to see that our help is always in him† (American Literature). Puritans saw God in everything; God gave them trials and tribulations so they could learn to be humble and meek. From the capture of Mary Rowlandson, to Anne Bradstre et’s personal poems, we can see how much God had influence on their every thought, and every action.The Fundamentalist thinkers of the Enlightenment saw things quite differently. They believed that writing was a method for recording logical reasoning, and often provoked rational thought. The Enlightenment era was a new intellectual movement that stressed reason and thought and the power of individuals to solve problems. Even though different philosophers approached their goals differently, they achieved it none the less. They all approached their goal differently due to their different upbringings, their different backgrounds, and most importantly their different environments.The Enlightenment period was known as the Age of Reason. Deism was a belief that God was impartial and there was no revealed religion to select body of people. Many believed that the rights belonged to the people. For example, John Locke believed that citizens were entitled to set of natural rights. John Locke’s philosophies and the ideas of the Enlightenment influenced Thomas Jefferson to write the Declaration of Independence. The document uses the idea of the Natural Law and justifies the reasons for escaping Great Britain’s rule.Benjamin Franklin and Thomas Paine wrote volumes on topics that questioned life, and the means by which one should live. Though there are a few small similarities between the writings of the two periods, there are considerably greater numbers of differences. Though the views of Puritans and Fundamentalists were dramatically different, they both believed in a certain code of morals and ethics. In both the Common Sense and The Crisis, No. 1. Thomas Paine uses metaphors to persuade the American Public to continue supporting the Revolutionary war in The Crisis.Thomas Paine implements powerful metaphors to achieve the effect. In the Common Sense used literary style intended to appeal to the broad masses of people rather than the elect few. Throu ghout his writing there is an emphasis upon the independence of the individual. In the beginning of the Crisis #1 the document begins with the telescopic sentence: â€Å" THESE are the times that try men’s souls,† which is contrary to the rest of the sentence lengths he uses.This makes the beginning omnipoint and interest the reader right off the get go. He uses capital letters to emphasize words such as freedom, tax, and bind when first presenting his argument. He also introduces strong negative diction, such as celestial and impious, that will continue throughout his writing. Paine’s writing was simple and direct, and his arguments turned on one or two accessible principles and pursued persuasion through clarity and repetition. j